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  • Title: [Effect of oxygen in different concentrations and free radical-anti-radical activity system in patients with chronic pulmonary insufficiency].
    Author: Aleksandrov OV, Vinitskaia RS, Naumenko ZK, Nekliudova GV.
    Journal: Klin Med (Mosk); 1997; 75(2):31-3. PubMed ID: 9157211.
    Abstract:
    The study of free-radical processes elucidated concentrations of O2 producing a negative effect in chronic obstructive bronchitis sufferers with respiratory insufficiency (RI). In RI of the second and third degree concentration of inhaled O2 should not exceed 50%. In this concentration O2 toxicity is not evident, unbalance of the system free radical-antiradical activity is less pronounced, O2 transport from the lungs to the tissue reaches optimal level. A course of oxygen therapy (20 daily sessions lasting 30 min., 50% O2) is not toxic, promoted activation of SOD and alleviation of arterial hypoxemia.
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