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  • Title: [Poems syndrome: a case report].
    Author: Tellería A, Hernández-González E, Gómez-Fernández L, Mustelier R, Calzada-Sierra D.
    Journal: Rev Neurol; 1997 Apr; 25(140):565-8. PubMed ID: 9172922.
    Abstract:
    INTRODUCTION: The Poems syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammapathy and skin changes) is an uncommon multisystemic disorder. Usually it is a manifestation of a type of myeloma of which the chief characteristic is the presence of osteosclerotic lesions, classically seen radiologically to be single or multiple. Nowadays, not only is Poems considered to be a manifestation of osteosclerotic myeloma, but may also be seen associated with other plasma cell dyscrasias. CLINICAL CASE: We present a case of Poems syndrome secondary to a plasmocytoma of the dorsal vertebral column in a 32 year old male negro. Initially he had sensori-motor polyneuropathy associated with other features characteristic of the syndrome (organomegaly, IgA monoclonal gammapathy and skin changes). Later he also showed signs attributed to a compressive lesion of the dorsal spinal medulla. An unusual finding in this patient was that the bony lesion was predominantly osteoclytic. CONCLUSIONS: We briefly review the syndrome and comment on the diagnosis.
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