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Title: Oral granular cell tumours: a histological and immunocytochemical study. Author: Williams HK, Williams DM. Journal: J Oral Pathol Med; 1997 Apr; 26(4):164-9. PubMed ID: 9176790. Abstract: In a series of nine cases of intra-oral granular cell tumors (GCTs) an attempt was made, using both histochemical and immunocytochemical methods, to determine whether these tumours show Schwann-cell or neuroendocrine differentiation. Positive immunostaining with protein gene product 9.5 (PGP 9.5), neurone-specific enolase (NSE) and S-100, in contrast to predominantly negative immunostaining in 12 cases of neurilemmoma of the head and neck, and a similar pattern of staining with luxol fast blue to five known neuroendocrine tumours, strongly suggests that granular cell tumors may be neuroendocrine in nature.[Abstract] [Full Text] [Related] [New Search]