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  • Title: [Amiodarone-induced thyrotoxicosis cured by thyroidectomy].
    Author: Le Cosquer P, Guerin-Robardey AM, Ossart M.
    Journal: Ann Fr Anesth Reanim; 1996; 15(7):1092-4. PubMed ID: 9180986.
    Abstract:
    We report a case of amiodarone-induced thyrotoxicosis, diagnosed with a systematic laboratory investigation in a 64-year-old patient, for haematuria. Despite the interruption of amiodarone, hyperthyroidism and a goiter occurred. Conventional therapy betablockers, antithyroid agents, prednisone, potassium perchlorate) did not result in any clinical improvement. The development of a malignant thyrotoxicosis with neurologic disturbances and acute respiratory insufficiency required mechanical ventilation and a subtotal thyroidectomy. The patient's status improved progressively and he was discharged without sequelae. The respective roles of medical therapy and thyroidectomy in amiodarone-induced thyrotoxicosis are discussed.
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