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  • Title: [Protective effect of pyridoxilate on the hypoxic myocardium. Experimental studies].
    Author: Moret PR, Lutzen U.
    Journal: Schweiz Med Wochenschr; 1977 Nov 05; 107(44):1585-6. PubMed ID: 918622.
    Abstract:
    The protective action of piridoxilate on hypoxic myocardium has been studied on rats in acute hypoxia (isolated heart, perfused with a non-oxygenated solution) and in prolonged hypoxia (3 days at high [3454 m] altitude). Piridoxilate maintained a higher ATP level with a much lower production of lactate. The mechanisms of action of piridoxilate are probably fairly similar to those of Na dichloracetate.
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