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  • Title: TUR syndrome and endoscopic transanal resection: no evidence for a clinically important association in 38 procedures.
    Author: Boyle JR, Thompson MM, Lopez B, Twist MH, Kelly MJ.
    Journal: Br J Surg; 1997 Jun; 84(6):831-3. PubMed ID: 9189102.
    Abstract:
    BACKGROUND: The TUR syndrome is well described after transurethral resection of the prostate. Endoscopic transanal resection (ETAR) is increasingly used to remove rectal lesions. METHODS: A prospective study of 38 ETARs in 21 patients was carried out over 2 years. Each patient was observed for symptoms and signs of TUR syndrome, and each had serial venous blood sampling and subsequent biochemical and haematological analysis during the perioperative period. RESULTS: No symptoms or signs typical of TUR syndrome were recorded. However, analysis of the biochemical variables using the Kruskal-Wallis one-way analysis of variance showed that there were statistically significant (P < 0.05) subclinical changes during the 24 h following the procedure affecting levels of serum sodium, potassium, total protein, albumin, lactate dehydrogenase, glycine, ammonia and serum osmolality. CONCLUSION: The changes in the electrolyte concentrations, although statistically significant, were not of the same magnitude as described previously in the TUR syndrome. The risk of a TUR-type syndrome in ETAR is small and serial blood tests, as detailed above, may safely be omitted.
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