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  • Title: Chondrosarcoma of the nasal cavity, paranasal sinuses, and nasopharynx.
    Author: Coates HL, Pearson BW, Devine KD, Unni KK.
    Journal: Trans Sect Otolaryngol Am Acad Ophthalmol Otolaryngol; 1977; 84(5):ORL919-26. PubMed ID: 919163.
    Abstract:
    Thirteen patients, six men and seven women, were seen at the Mayo Clinic with chondrosarcomas of the nasal cavity, paranasal sinuses, or nasopharynx in a 25-year period. Nasal obstruction, discharge, and bleeding were the major symptoms and a nasal mass was the most common sign. The typical chondrosarcoma is low in grade but malignant and it arises in the nasal cavity as a large, pale, glistening mass. Local excision was employed initially in seven patients and five had local recurrence. Definitive block excision cured four of six patients and the two others had a protracted clinical course and ultimately died of the disease. Long-term follow-up shows that chondrosarcomas are insidious, locally progressive tumors. Radiotherapy, used for palliation after recurrence, failed to produce any cures. Lateral rhinotomy and block excision are advocated as the primary treatment.
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