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  • Title: Effect of some environmental factors on the content and composition of microbial membrane lipids.
    Author: Sajbidor J.
    Journal: Crit Rev Biotechnol; 1997; 17(2):87-103. PubMed ID: 9192472.
    Abstract:
    Lipids are known as a part of an effective adaptation mechanism reflecting the changes in the extracellular environment. The fluidity of biological membranes is influenced by the lipid structure and the portion of saturated, unsaturated, branched, or cyclic fatty acids in individual phospholipids. For all living organisms undergoing environmental adaptation, the fluidity can be changed only to a relatively small extent. This range is genetically determined and it is specific for every microorganism. This article presents recent knowledge about the influence of some environmental parameters (temperature, osmotic pressure, pH, the presence of salt or ethanol in medium) on a microbial membrane with the emphasis on regulation aspect in fatty acid biosynthesis. The main tools for regulation of membrane fluidity, for example, fatty acid desaturation or incorporation of branched and cyclic fatty acids into phospholipids, are discussed in more detail.
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