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  • Title: Pathogenesis of non-traumatic atlanto-axial subluxation (Grisel's syndrome).
    Author: Welinder NR, Hoffmann P, Håkansson S.
    Journal: Eur Arch Otorhinolaryngol; 1997; 254(5):251-4. PubMed ID: 9195151.
    Abstract:
    Non-traumatic atlanto-axial subluxation (AAS) is an uncommon complication of upper neck inflammatory processes and head and neck surgery. It is also known under the eponym of Grisel's syndrome (GS). We present a case report of a 6-year-old boy with GS that resulted from a retropharyngeal abscess. A diagnosis was not made until 2 months after the occurrence of infection. Re-evaluation of repeated CT scans of the neck showed the sequential development of AAS. These findings implied that the pathogenesis of GS is a distention of the ligaments between the atlas and axis rather than loosening of the ligaments caused by the spread of an inflammatory edema from the soft tissues of the neck as has been proposed by others.
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