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  • Title: [Stress ulcer-an experimental study (author's transl)].
    Author: Kokoschka R, Göber I, Gebhart W.
    Journal: Wien Klin Wochenschr; 1977 Sep 02; 89(16):553-62. PubMed ID: 919554.
    Abstract:
    This experimental study demonstrates by means of electromagnetic flow measurements that hypovolaemic shock results in a significant decrease in gastric flow. 14 mongrel dogs were subjected to haemorrhagic shock for 3 or 4 hours. Significant histological changes are seen in the gastric mucosa as a result of the haemodynamic changes, especially when the duration of shock was 4 hours. All stages of stress ulcer from the superficial erosion to deep ulcers were documented. The possibility that the mast cell plays a pathogenetic role as mediator in the origination of a stress ulcer is considered.
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