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  • Title: [A study on changes of levels of products of lipid peroxidation in retina of rat with experimental autoimmune uveoretinitis].
    Author: Sun X, Zhang C.
    Journal: Zhonghua Yan Ke Za Zhi; 1996 Mar; 32(2):140-2. PubMed ID: 9206234.
    Abstract:
    OBJECTIVE: To understand the mechanisms of the retinal tissue destruction of rat with experimental autommune uveoretinitis (EAU) induced by rabbit retinal soluble antigen. METHOD: The levels of the following products of lipid peroxidation were determined at different times, conjugated dienes, malondialdehyde, fluorochrome lipid and lipid hydrogen peroxide. RESULTS: In the process of EAU, the levels of products of lipid peroxidation in the retina were increased gradually in various degrees. CONCLUSION: It is suggested that the damage from lipid peroxidation mediated by free radicals of the retina be one of the factors which induces the retinal destruction in EAU.
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