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  • Title: [Hematologic manifestations related to hepatitis A virus. 3 cases].
    Author: Maiga MY, Oberti F, Rifflet H, Ifrah N, Calès P.
    Journal: Gastroenterol Clin Biol; 1997; 21(4):327-30. PubMed ID: 9207999.
    Abstract:
    We report 3 cases of acute hepatitis A infection with haematological manifestations. In the first case, severe aplastic anemia occurred in a 6 year-old child, who underwent 3 bone marrow grafts before responding favourably. In the second and third cases, severe anemia and thrombocytopenia occurred in a 42 year-old man with cholestatic hepatitis, and in a 66 year-old man with fulminant hepatitis; there was a favourable outcome in both cases. These cases demonstrate that haematological manifestations in hepatitis A can be severe, independent of the severity of liver disease. Although these manifestations seem to be rare, we suggest performing systematic haematological evaluations in cases of viral hepatitis A with unusual outcomes.
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