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Title: Cytotoxic and antiplatelet aggregation principles from Aglaia elliptifolia. Author: Wu TS, Liou MJ, Kuoh CS, Teng CM, Nagao T, Lee KH. Journal: J Nat Prod; 1997 Jun; 60(6):606-8. PubMed ID: 9214732. Abstract: Two related 1H-2,3,3a,8b-tetrahydrocyclopenta[b]benzofurans, aglafolin (1a) and rocaglamide (2), isolated from the stems of Aglaia elliptifolia, showed significant cytotoxicity in six cancer cell lines. Aglafolin (1a) was also found to completely block platelet aggregation caused by arachidonic acid and platelet-activating factor at 100 microM and 2 ng/mL, respectively.[Abstract] [Full Text] [Related] [New Search]