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  • Title: Development and efficacy of a vaccine against Streptococcus iniae infection in farmed rainbow trout.
    Author: Eldar A, Horovitcz A, Bercovier H.
    Journal: Vet Immunol Immunopathol; 1997 May; 56(1-2):175-83. PubMed ID: 9220590.
    Abstract:
    Formalin killed bacteria were used as a vaccine against Streptococcus iniae infections in farmed rainbow trout. A single intraperitoneal injection of this vaccine in trout resulted in specific antibody production detectable for 6 months. Trout vaccinated at 50 g were protected under laboratory (experimental disease) and field conditions (natural disease) for at least 4 months against S. iniae infection. Passive transfer of S. iniae specific antibodies conferred protection. Under field conditions, mortality of non vaccinated trout exceeded 50%, whereas mortality of vaccinated trout did not reach 5%. In addition, vaccinated trout under field conditions gained 20% weight when compared with non vaccinated fish.
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