These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Enzyme therapy in children with severe forms of Gaucher's disease].
    Author: Zeman J, Hrebícek M, Vepreková L, Kytnarová J, Houstková H, Malinová V, Hodanová K, Poupĕtová H, Ledvinová J, Hoza J.
    Journal: Cas Lek Cesk; 1997 Feb 05; 136(3):95-7. PubMed ID: 9221177.
    Abstract:
    The enzyme therapy with Ceredase in patients with Gaucher's disease is at present probably the most expensive treatment in the whole world. One-year treatment of an adult patient with Gaucher's disease costs more than 7 million crowns. Indications for treatment in individual patients as well as financial provisions are so far problematic in the Czech Republic. From a total of 28 patients of varying age with Gaucher's disease diagnosed by the authors Ceredase was administered to two boys with a severe course of the disease. Within one year of treatment the health status of both children improved, growth became normal, the spleen diminished in size by 20-35%, haematological manifestations of hypersplenism are receding, there was a 32-46% decline of the activity of serum chitotriosidase and biochemical parameters of the disease improved.
    [Abstract] [Full Text] [Related] [New Search]