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Title: Medullary thyroid carcinoma: one component of the inherited disorder multiple endocrine neoplasia type 2A. Author: Giarelli E. Journal: Oncol Nurs Forum; 1997 Jul; 24(6):1007-20; quiz 1021-2. PubMed ID: 9243586. Abstract: PURPOSE/OBJECTIVES: To describe and discuss the inherited syndrome multiple endocrine neoplasia (MEN) and one of its components medullary thyroid carcinoma. DATA SOURCES: Published books and articles; clinical experience. DATA SYNTHESIS: Three distinct types of MEN are known. Type 2a consists of medullary thyroid carcinoma, pheochromocytoma, and other conditions. The disorder is autosomal-dominant. Genetic counseling and screening and biochemical screening are possible. Early detection and treatment are key to successful control. CONCLUSIONS: Identification of kindreds affected by this inherited disorder can result in improved detection and early treatment. The merit and value of presumptive treatment remain unclear. IMPLICATIONS FOR NURSING PRACTISE: Nursing activities encompass prediagnosis through postoperative phases. Care involves all members of the family as well as psychological care.[Abstract] [Full Text] [Related] [New Search]