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  • Title: Granuloma formation in lungs of mice after intravenous administration of emulsified trehalose-6,6'-dimycolate (cord factor): reaction intensity depends on size distribution of the oil droplets.
    Author: Yarkoni E, Rapp HJ.
    Journal: Infect Immun; 1977 Nov; 18(2):552-4. PubMed ID: 924683.
    Abstract:
    The intensity of the granulomatous reaction evoked in lungs of mice by trehalose-6,6'-dimycolate administered intravenously in oil-water emulsion depended on the size distribution of the oil droplets. Emulsions containing the greatest number of the largest oil droplets were the most granulomagenic.
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