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  • Title: Isolation of a new Orientia tsutsugamushi serotype.
    Author: Seong SY, Park SG, Kim HR, Han TH, Kang JS, Choi MS, Kim IS, Chang WH.
    Journal: Microbiol Immunol; 1997; 41(6):437-43. PubMed ID: 9251054.
    Abstract:
    Orientia tsutsugamushi, the etiological agent of scrub typhus, is an antigenically diverse organism and many serologically distinct strains have been identified. The 56 kDa protein of O. tsutsugamushi, a major protein in the outer membrane, has been thought to be responsible for this antigenic variability. A strain of O. tsutsugamushi isolated in Korea cross-reacted with both Gilliam strain-specific and Karp strain-specific monoclonal antibodies. When its 56 kDa protein gene was cloned and analyzed, its sequence showed variation especially between 1,200 and 1,250 bp, showing that this isolate is a new O. tsutsugamushi strain.
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