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  • Title: The importance of plasma polymorphonuclear (PMN) elastase determination in patients with uveitis.
    Author: Akyol N, Değer O, Erdöl H, Gedik Y, Orem A, Imamoglu HI.
    Journal: Acta Ophthalmol Scand; 1997 Jun; 75(3):287-9. PubMed ID: 9253976.
    Abstract:
    PURPOSE: Polymorphonuclear elastase is used as an important marker for inflammatory disease. We wanted to show whether polymorphonuclear elastase could be a marker in uveitis. METHODS: Twenty-two patients with uveitis and 30 healthy control subjects were included in the study. Polymorphonuclear elastase levels were determined by immunoactivation method before and after periods of corticosteroid and/or cyclosporin treatments. RESULTS: The levels were high in all of the patients before treatment; the levels reached normal range with treatment. In some cases, however, uveitis could not be suppressed in spite of treatment; these patients had high polymorphonuclear elastase levels. CONCLUSION: It was concluded that determination of polymorphonuclear elastase level may be used for monitoring of uveitis.
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