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  • Title: Synchronized Plasmodium yoelii yoelii: pattern of gametocyte production, sequestration and infectivity.
    Author: Gautret P, Miltgen F, Chabaud AG, Landau I.
    Journal: Parassitologia; 1996 Dec; 38(3):575-7. PubMed ID: 9257348.
    Abstract:
    The chronobiology of the gametocytes of P. yoelii was studied in Percoll-glucose synchronized infection in the mouse. The gametocyte developmental cycle consisted of 4 successive stages: stage 0 maturation took 27 hours from merozoite invasion, stage 0 to stage 1 lasted 6 hours, stage I to stage II and stage II to stage III lasted 3 hours each. Stage 0 gametocytes were found to sequester in small peripheral capillaries, and the number of oocysts in mosquitoes was related to the number of stage 0 gametocytes ingested.
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