These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Minimal haemolysis in blood co-infused with amino acid and dextrose solutions in vitro.
    Author: Jankov RP, Roy RN.
    Journal: J Paediatr Child Health; 1997 Jun; 33(3):250-2. PubMed ID: 9259303.
    Abstract:
    OBJECTIVE: To examine the haemolytic effects of amino acid and dextrose solutions on co-infused packed red blood cells. METHODOLOGY: An in vitro study of packed cells co-infused at various rates with dextrose 5%, 10%, 15% and intravenous amino acid solution (Vamin; Kabi-Pharmacia, Baxter Healthcare Pty Ltd) in dextrose 5%, 10% and 15%. The degree of haemolysis was measured as free oxyhaemoglobin by spectrophotometer. Co-infused 0.9% saline and water were used as 0% and 100% haemolysis controls. RESULTS: Only minimal haemolysis was observed with the solutions tested. The greatest observed amount of haemolysis was 0.14%. CONCLUSIONS: Co-infusion of packed red blood cells with dextrose and amino acid solutions at the concentrations and infusion rates commonly used in neonatal care, does not cause clinically important haemolysis.
    [Abstract] [Full Text] [Related] [New Search]