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  • Title: Foramen thyroideum: a comparative study in embryos, fetuses, and adults.
    Author: León X, Maranillo E, Mirapeix RM, Quer M, Sañudo JR.
    Journal: Laryngoscope; 1997 Aug; 107(8):1146-50. PubMed ID: 9261024.
    Abstract:
    The incidence and characteristics of foramen thyroideum (FT) in embryonic and/or fetal larynges have not been established. In the present study, 90 adult larynges and 53 embryonic-fetal larynges were studied. The incidence of FT during the embryonic-fetal period (57%) was statistically different from the adult period (31%) (P = 0.005). All the FT found in the adult period contained vessels and/or nerves, while in the embryonic and fetal period only 63% presented neurovascular elements (P < 0.001). The origin of FT in the embryonic period and its persistence during adult life is discussed.
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