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  • Title: Posttransplantation lymphoproliferative disorder in a renal allograft recipient.
    Author: Goral S, Felgar R, Shappell S.
    Journal: Am J Kidney Dis; 1997 Aug; 30(2):301-7. PubMed ID: 9261047.
    Abstract:
    As a complication of immunosuppressive therapy, solid organ and bone marrow transplant recipients have an increased risk of developing post transplant lymphoproliferative disorder (PTLD). Epstein-Barr virus (EBV) infection and the degree of immunosuppression have been identified as risk factors for the development of this complication. The clinical presentation includes a spectrum of disorders ranging from a benign infectious mononucleosis-like syndrome with fever and cervical adenopathy to multiorgan failure leading to death. Although, T-cell lesions have been described, PTLD is usually associated with a polyclonal or monoclonal B-cell proliferation. In this report, we present a renal transplant recipient with a perirenal mass diagnosed as PTLD.
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