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  • Title: Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectoris.
    Author: Ceremuzyński L, Chamiec T, Herbaczyńska-Cedro K.
    Journal: Am J Cardiol; 1997 Aug 01; 80(3):331-3. PubMed ID: 9264427.
    Abstract:
    A randomized, double-blind, placebo-controlled study in patients with clinical symptoms of stable angina pectoris and healed myocardial infarction (n = 22) has shown that oral supplementation with L-arginine (6 g/day for 3 days) increases exercise capacity (tested on a Marquette case 12 treadmill according to the modified Bruce protocol). Results suggest that the inefficient L-arginine/nitric oxide system contributes to limitation of myocardial perfusion and/or peripheral vasodilation during maximum exercise in patients with stable angina pectoris.
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