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  • Title: Reverse micellar extraction of antibiotics from aqueous solutions.
    Author: Fadnavis NW, Satyavathi B, Deshpande AA.
    Journal: Biotechnol Prog; 1997; 13(4):503-5. PubMed ID: 9265783.
    Abstract:
    Several antibiotics such as erythromycin, oxytetracyclin, benzylpenicillin, and actidione were extracted from aqueous buffers into reverse micellar solution of bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) in isooctane and recovered with high efficiency under mild conditions. Preliminary experiments with oxytetracycline dissolved in a fermentation broth indicate that the antibiotic can be selectively extracted from the broth and recovered efficiently without serious loss of potency.
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