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  • Title: Sarcomatoid chromophobe cell renal carcinoma: immunohistochemical and lectin study in one case.
    Author: Gómez-Román JJ, Mayorga-Fernández M, Fernández-Fernández F, Val-Bernal JF.
    Journal: Gen Diagn Pathol; 1997 Jul; 143(1):63-9. PubMed ID: 9269910.
    Abstract:
    We present one case of sarcomatoid chromophobe cell renal carcinoma with an indolent clinical course and assume that the carcinomatous component may affect the biologic behavior. The patient was a 61-year-old man who underwent right radical nephrectomy for a 11.2 cm tumor in the lower pole. The immunohistochemical findings demonstrate that EMA and cytokeratins 8 and 18 are useful markers for the sarcomatoid fraction, and the lectin study shows a loss of surface blood antigen. Chromophobe cell carcinoma may convert into sarcomatoid carcinoma. The existence of sarcomatoid renal cell carcinoma as a distinct entity should be re-considered.
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