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  • Title: Effects of various types of Triton X on the susceptibilities of methicillin-resistant staphylococci to oxacillin.
    Author: Suzuki J, Komatsuzawa H, Sugai M, Ohta K, Kozai K, Nagasaka N, Suginaka H.
    Journal: FEMS Microbiol Lett; 1997 Aug 15; 153(2):327-31. PubMed ID: 9271859.
    Abstract:
    We examined the effect of six types of the nonionic detergent Triton X on the susceptibilities of methicillin-resistant staphylococci to oxacillin. We used five methicillin-resistant Staphylococcus aureus isolates and 17 methicillin-resistant coagulase-negative staphylococci isolates. All strains of S. aureus, S. epidermidis and S. sciuri had enhanced susceptibility to oxacillin following exposure to the types of Triton X having 7-13 polymerized ethylene oxides. These strains were altered from homogeneously resistant to heterogeneously resistant by Triton X-100. Those types of Triton X that affected the resistance level also promoted the release of lipoteichoic acid. These results and those of previous studies suggest that Triton X might act on factors other than the mecA or femA products.
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