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  • Title: [Importance of toxicological studies in animals for elaboration of pathogenetic therapy of hydrazine intoxication].
    Author: Baryshnikov II.
    Journal: Med Tr Prom Ekol; 1997; (6):22-5. PubMed ID: 9273132.
    Abstract:
    Pathogenesis of poisoning with hydrazine seems complicated. Hydrazines inhibit pyridoxal-dependent enzymes, interfere with carbohydrates transformation and lipid metabolism, alter the processes of energy metabolism. Treatment of poisoning with hydrazine is effective only when containing drug combinations. Based experimentally, recommendations on the combination (phenazepam, be methyl, piracetam, ionol) were supported by chemical testing of the drugs.
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