These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Lipid peroxidation as a toxic mode of action for lead and cadmium].
    Author: Skoczyńska A.
    Journal: Med Pr; 1997; 48(2):197-203. PubMed ID: 9273442.
    Abstract:
    Recent studies have shown that lead and cadmium deplete glutathione and protein-bound sulfhydryl groups, resulting in the production of reactive oxygen species. As a consequence enhanced lipid peroxidation, DNA damage and altered calcium and sulfhydryl homeostasis occur. Lipid peroxidation is often discussed as a cause of metal-induced toxicity, although many other authors suggest a pivotal role of interaction with sensitive SH groups in determining cadmium and lead toxicity.
    [Abstract] [Full Text] [Related] [New Search]