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  • Title: [Influence of lead on metabolism of vitamins B group in alimentary iron deficient rats].
    Author: Khotimchenko SA, Kodentsova VM, Alekseeva IA, Vlaskina SG, Vrzhesinskaia OA, Sokol'nikov AA, Kharitonchik LA, Aleshko-Ozhevskií IP, Sheviakova LV.
    Journal: Vopr Med Khim; 1997; 43(3):158-64. PubMed ID: 9273779.
    Abstract:
    Experimentally induced lead poisoning especially under simultaneous iron deficit leads to the development of secondary thiamine insufficiency. Erythrocyte riboflavin content and erythrocyte glutathion reductase and aspartate aminotransferase activities have been demonstrated to be increased. Lead treatment is accompanied with the increase of urinary excretion of riboflavin, 4-pyridoxic acid and 1-vtthylnicotinamide in rats fed with adequate diet. Thus lead intoxication and iron deficiency influence vitamin B group metabolism.
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