These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Expression of carbonic anhydrase IV in carbonic anhydrase II-deficient mice.
    Author: Brion LP, Cammer W, Satlin LM, Suarez C, Zavilowitz BJ, Schuster VL.
    Journal: Am J Physiol; 1997 Aug; 273(2 Pt 2):F234-45. PubMed ID: 9277584.
    Abstract:
    Chronic metabolic acidosis (CMA) in the rabbit upregulates carbonic anhydrase (CA) IV in the proximal convoluted tubule (PCT). This study was designed to assess CA IV expression in a model of CMA in the mouse, i.e., congenital deficiency in CA II [CA(II)D]. In female CA(II)D mice, CA IV specific activity but not CA IV immunoreactivity was upregulated in the renal cortex, specifically in microdissected PCTs. Western blot analysis showed higher expression of CA IV immunoreactive protein in renal membranes from males than in those from females.
    [Abstract] [Full Text] [Related] [New Search]