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  • Title: Amniotic fluid lecithin/sphingomyelin ratio changes related to centrifugal force.
    Author: Cherayil GD, Wilkinson EJ, Borkowf HI.
    Journal: Obstet Gynecol; 1977 Dec; 50(6):682-8. PubMed ID: 927759.
    Abstract:
    Lecithin/sphingomyelin ratio (L/S ratio) in amniotic fluid has gained wide clinical acceptance as an index of fetal lung maturity. We determined L/S ratios of amniotic fluids centrifuged at various "g-forces." Our studies demonstrate that the L/S ratio value is highly dependent on the g-force used to prepare the fluid. We recommend standardization of the g-force, time, and temperature used in preparation of the amniotic fluid for L/S ratio determination.
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