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  • Title: Efficiency of praziquantel, a new cesticide, against Taenia hydatigena in the dog.
    Author: Baldock FC, Flucke WJ, Hopkins TJ.
    Journal: Res Vet Sci; 1977 Sep; 23(2):237-8. PubMed ID: 928986.
    Abstract:
    Praziquantel (2 - cyclohexylcarbonyl - 1,3,4,6,7,11b - hexahydro - 2H - pyrazino (2,1 - a) isoquinolin - 4 - one) was tested against artificially established infections of Taenia hydatigena in 39 dogs. The formulation used was a 660 mg tablet containing 50 mg of active ingredient (ai). A single oral dose at 1 mg/kg ai completely removed 14-day-old infections in all dogs. 2.5 mg/kg ai praziquantel was completely effective against 7, 14 and 28-day-old worms. 5 mg/kg ai completely removed two-day-old infestations. No side effects were seen in any treated dog.
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