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  • Title: Toxic shock-like syndrome caused by non-group A beta-hemolytic streptococci.
    Author: Hirose Y, Yagi K, Honda H, Shibuya H, Okazaki E.
    Journal: Arch Intern Med; 1997 Sep 08; 157(16):1891-4. PubMed ID: 9290550.
    Abstract:
    Two patients with rapidly developing shock, multisystem organ failure, and destructive soft-tissue infection caused by groups G and C streptococci are described. Both patients died rapidly despite aggressive treatment. The clinical characteristics cannot be distinguished from those of toxic shock-like syndrome, but Streptococcus pyogenes was not recovered. These strains did not produce any previously identified type of streptococcal pyrogenic exotoxins. These findings suggest that toxic shock-like syndrome can be caused not only by group A but also groups G and C streptococci. The causative strains of toxic shock-like syndrome may have something in common with unknown virulent factors for this syndrome.
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