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  • Title: Construction of chimeric phages and plasmids containing the origin of replication of bacteriophage lambda.
    Author: Moore DD, Denniston-Thompson K, Furth ME, Williams BG, Blattner FR.
    Journal: Science; 1977 Dec 09; 198(4321):1041-6. PubMed ID: 929185.
    Abstract:
    Segments of the replication control region of bacteriophage lambda (lambda) and lambda mutants defective in replication were attached in vitro to the phi80 phage vector Charon 3 and to the plasmid vector mini Col El (pVH51). The chimeric phages and plasmids have been used to localize the origin of lambda DNA replication and to facilitate a structural analysis of the lambda replicator.
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