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  • Title: Knowledge representation for computer-aided planning of controlled clinical trials: the PATriCIa project.
    Author: Haag U.
    Journal: Methods Inf Med; 1997 Aug; 36(3):172-8. PubMed ID: 9293715.
    Abstract:
    The main thesis of the PATriCIa project is that a knowledge-based system can provide efficient and reliable support for biometricians as well as physicians involved in planning of controlled clinical trials, resulting in a higher quality of medical research. Structure and contents of study protocols are analyzed, and an object-oriented method for formally representing biometric knowledge is proposed. A study protocol can be generated from this formal representation. The programming language Prolog is used to realize the system based on a blackboard architecture. It is concluded that the knowledge representation method developed in the PATriCIa project is well suited for the purpose of generating study protocols for controlled clinical trials.
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