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  • Title: [Pseudotumor form of hepatic distomatosis: successful treatment with praziquantel].
    Author: Queneau PE, Koch S, Bresson-Hadni S, Bartholomot B, Arbez-Gindre F, Heyd B, Miguet JP.
    Journal: Gastroenterol Clin Biol; 1997; 21(6-7):511-3. PubMed ID: 9295980.
    Abstract:
    Human Fasciola hepatica infection is usually discovered either early, during the acute (invasive) phase, or in the advanced phase, which is characterized by biliary complications. We report a case of liver distomatosis with nodular intra-hepatic lesions in a 58-year-old woman. Radiological investigations showed 3 nodular lesions in the VII segment, which were difficult to distinguish from liver metastases or liver abscesses. Distomatosis serology was positive with passive hemagglutination. After a 5-day treatment with praziquantel, clinical symptoms resolved quickly while serological tests became negative. Radiological images slowly decreased to a calcified scar at 13 months. No side-effects were noted. Praziquantel, whose efficacy in the common presentations of liver distomatosis has recently been demonstrated, also seems effective and well tolerated in case of nodular intra-hepatic lesions.
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