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  • Title: [Agenesis of the corpus callosum: modes of manifestation in adults].
    Author: Lemesle M, Giroud M, Madinier G, Martin D, Baudouin N, Binnert D, Dumas R.
    Journal: Rev Neurol (Paris); 1997 May; 153(4):256-61. PubMed ID: 9296144.
    Abstract:
    Agenesis of corpus callosum is an uncommon brain malformation that is usually detected in childhood. In adult, focal epileptic seizure is the most frequent manifestation. Otherwise, asymptomatic patients can be detected by cerebral imagery with specific criteria. Neither developmental disability nor interhemispheric transfer dysfunction are observed in those patients. Minor facial abnormalities can be found. Agenesis of corpus callosum in adult is usually paucisymptomatic. The prognosis depends on cerebral associated malformations which are involved in epilepsy and cognitive disturbances.
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