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  • Title: 1,3-Dimethylpyrimidoheterocycles as antibacterial agents.
    Author: Zoorob HH, Abou Elzahab M, Abdel-Mogib M, Ismail MA, Abdel-Hamid M.
    Journal: Arzneimittelforschung; 1997 Aug; 47(8):958-62. PubMed ID: 9296283.
    Abstract:
    1,3-Dimethylbarbituric acid was used as a versatile precursor for the preparation of annelated pyranopyrimidines 2 and 3a-c besides pyrrolopyrimidine 12. The isolated pyrazolopyrimidines 8a-c and 10 and fused pyrazolopyrimidines 14a-d were also synthesized. In addition the new obtained pyrimidoheterocycles were subjected to bacterial testings.
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