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  • Title: [Dynamics of RNA concentration in different CNS structures following audiogenic seizures].
    Author: Khaĭdarliu SKh, Makoveev VI.
    Journal: Tsitologiia; 1977 Sep; 19(9):1058-62. PubMed ID: 929695.
    Abstract:
    By means of morpho- and cytospectrophotometrical analysis, the influence of audiogenic seizures in genetically predisposed rats on RNA content in individual cells of four different neuron-glia systems was studied. RNA content was chaaracterized by different dynamics and pronounciation of changes and duration of restitution period. The most expressed disturbances were found in the second layer of the temporal cortex. Shifts in RNA content were preserved, as a rule, for 24 hours, but in glial cells of the cerebellar cortex and anterior horn of the spinal cord they lasted for 48 hours after cessation of the seizures. Metabolic interralations between nerve and glial cells of different regions of the central nervous system are characterized by some essential peculiaritis depending on the degree of involvement of concrete nervous structure in realization of seizures, its structural, metabolic and functional characteristics.
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