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  • Title: Idiopathic myelofibrosis with neutrophil myeloperoxidase deficiency: a case report.
    Author: Caenazzo A, Piva E, Sartori D, Stefani PM.
    Journal: Haematologica; 1997; 82(4):465-7. PubMed ID: 9299865.
    Abstract:
    We describe a case of idiopathic myelofibrosis with total neutrophil myeloperoxidase deficiency. The combination of this enzymatic defect with myelofibrotic changes in the nuclear shape of neutrophils confers a peculiar appearance on leukograms produced by a Technicon H*1. The clinical course of the disease was shortened by recurrent infections that may be ascribed, at least in part, to reduced leukocyte microbicidal ability.
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