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  • Title: Neurocutaneous melanosis with intracranial malignant melanoma in an adult: a case report.
    Author: Kimura H, Itoyama Y, Fujioka S, Ushio Y.
    Journal: No Shinkei Geka; 1997 Sep; 25(9):819-22. PubMed ID: 9300451.
    Abstract:
    A 65-year-old female with congenital giant, hairy and pigmented nevus developed sudden onset of headache and consciousness disturbance. CT scan revealed a high density mass in the right temporal subcortical region. The high density area suggested hematoma. A right temporal craniotomy was performed. Hemorrhage was observed in a black colored tumor. Histologically, the tumor was malignant melanoma, while the skin tumor was benign intradermal nevi. This patient was diagnosed as neurocutaneous melanosis. Neurocutaneous melanosis belongs to unusual congenital syndrome, and an adult case is very rare. To our knowledge this is the oldest patient to be reported with this disease.
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