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  • Title: Prophylaxis of experimental HTLV-I infection in cynomolgus monkeys by passive immunization.
    Author: Akari H, Suzuki T, Ikeda K, Hoshino H, Tomono T, Murotsuka T, Terao K, Ito H, Yoshikawa Y.
    Journal: Vaccine; 1997; 15(12-13):1391-5. PubMed ID: 9302750.
    Abstract:
    The protective effect of purified human immunoglobulin against human T-cell leukaemia virus type I (HTLV-I), designated ATLIG on HTLV-I infection was examined in cynomolgus monkeys (Macaca fascicularis) as a preclinical study. Passive immunization of ATLIG 24 h before challenging HTLV-I protected the monkeys from HTLV-I infection. The result suggests that passive immunization of ATLIG could provide safe and sufficient protection against HTLV-I infection in humans.
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