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  • Title: [APC, beta-catenin, DLG].
    Author: Akiyama T.
    Journal: Gan To Kagaku Ryoho; 1997 Sep; 24(11):1432-5. PubMed ID: 9309137.
    Abstract:
    The APC gene is mutated in the majority of colorectal tumors. The product of this gene is a 300 kDa protein associated with beta-catenin and the human homolog of the Drosophila tumor suppressor DLG. The study of the function of APC provides important insights into the mechanisms of the development of colorectal tumor.
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