These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Evaluation of Amplicor MTB PCR assay for the detection of Mycobacterium tuberculosis in specimens by means of negative direct microscopic examination].
    Author: Amrane H, Guessous S, Brugiere O.
    Journal: Pathol Biol (Paris); 1997 Jun; 45(6):479-82. PubMed ID: 9309263.
    Abstract:
    The reliability of the Roche Amplicor Mycobacterium tuberculosis test (Amplicor MTB) was evaluated by testing smear-negative specimens from patients with clinical and radiological characteristics of tuberculosis. A total of 364 clinical samples including biopsies and fluids from 153 patients was tested using the Amplicor MTB and the results were compared with those of culture. After discrepancy resolution and patients chart review, sensibility, specificity, positive predictive value and negative predictive value were 44.7%, 99.7%, 94.4% and 93.9% respectively. Our study indicates that Amplicor MTB, despite its low sensibility and for its high specificity can bring a valuable complement for improving the laboratory diagnosis of tuberculosis.
    [Abstract] [Full Text] [Related] [New Search]