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  • Title: [Autoregulation in ischemia of the optic nerve in the human].
    Author: Titzé P, Hero M, Petrig BL, Cranstoun SD, Riva CE.
    Journal: Klin Monbl Augenheilkd; 1997 May; 210(5):308-9. PubMed ID: 9324540.
    Abstract:
    BACKGROUND: Autoregulation is defined as the maintenance of constant blood flow in a vascular system in spite of changes in perfusion pressure (PPm). MATERIALS AND METHODS: PPm was decreased by increasing the intraocular pressure (IOP) with a suction cup and optic nerve blood flow was measured with the laser Doppler flowmetry technique (LDF) in 9 normal volunteers. RESULTS: The blood flow was autoregulated down to a PPm of 13 mm Hg (IOP = 47 mm Hg). CONCLUSIONS: These results confirm previous studies in cats and monkeys. The mechanism of autoregulation is probably a decrease in resistance due to capillary recruitment.
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