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  • Title: Reticalmin: a novel calcium/calmodulin-dependent protein kinase IV-like protein in rat retina.
    Author: Hirooka K, Tokuda M, Tsumura T, Ahmed BY, Itano T, Matsui H, Konishi R, Hasegawa E, Okuno S, Kitani T, Fujisawa H, Hatase O.
    Journal: Vision Res; 1997 Aug; 37(15):2029-33. PubMed ID: 9327050.
    Abstract:
    Western blot analysis of 100,000 g supernatant of rat retina using a polyclonal anti-Ca2+/ calmodulin-dependent protein kinase IV (CaM-kinase IV) antibody revealed an immunoreactive mass of 35 kDa, termed reticalmin. Lower amount of a isoform of CaM-kinase IV was also expressed in rat retina. Reticalmin did not react with anti-CaM-kinase IV C-terminal peptide antibody which recognized alpha and beta isoforms of CaM-kinase IV and calspermin. Immunohistochemically reticalmin was shown to be localized mainly in the outer segment of photo-receptor cells, and in dendrites of inner plexiform layers and may be in nuclei of ganglion cells and some inner nuclear layer cells.
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