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Title: The basal ganglia and cognitive pattern generators. Author: Graybiel AM. Journal: Schizophr Bull; 1997; 23(3):459-69. PubMed ID: 9327509. Abstract: This article introduces the notion of cognitive pattern generators and suggests, by analogy with the central pattern generators of the motor system, that these pattern generators operate to organize neural activity underlying aspects of action-oriented cognition. It is further proposed that the basal ganglia are involved in the control of cognitive as well as motor pattern generators. Disorders of the basal ganglia may thereby contribute to neural circuit dysfunctions that are expressed as positive and negative symptoms of schizophrenia.[Abstract] [Full Text] [Related] [New Search]