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  • Title: 'Sneeze syncope', basilar invagination and Arnold-Chiari type I malformation.
    Author: Corbett JJ, Butler AB, Kaufman B.
    Journal: J Neurol Neurosurg Psychiatry; 1976 Apr; 39(4):381-4. PubMed ID: 932754.
    Abstract:
    Syncope precipitated by sneezing in an adult male associated with an Arnold-Chiari type I malformation and basilar invagination presents a clinical problem in the differential diagnosis and pathological anatomy of Valsalva-related syncope. An abnormally acute clivoaxial angle, small foramen magnum, and type I Arnold-Chiari malformation appear to be a combination of features intolerant of Valsalva-induced changes in cerebral volume, brain-stem position, CSF fluid dynamics, or blood vessel relationships. Proposed mechanisms of pressure transmission to the area of intracranial pathology are discussed.
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