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  • Title: Isolation of 10, 11-epoxide of protriptyline in rat urine after protriptyline administration.
    Author: Rovei V, Belvedere G, Pantarotto C, Frigerio A.
    Journal: J Pharm Sci; 1976 Jun; 65(6):810-5. PubMed ID: 932963.
    Abstract:
    The 10, 11-epoxide, 10-hydroxy, and 10, 11-dihydrodiol metabolites of protriptyline were identified in rat urine collected after the administration of 40 mg/kg ip of protriptyline. Mass spectrometric characterization confirmed the structure of these metabolites.
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